科研之友
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摘要
Resistance to chemotherapy is one of the major causes of failure of anticancer treatment. It can occur at every level of the drug action and includes mechanisms such as increased drug efflux and decreased influx, drug inactivation, alterations in the drug target, DNA damage repair, and evasion of apoptosis. In this article some mechanisms of drug resistance in cancer chemotherapy are reviewed (Adv Clin Exp Med 2010, 19, 1, 5-12).
- 出版日期2010
