Annihilation Upconversion in Cells by Embedding the Dye System in Polymeric Nanocapsules

作者：Wohnhaas Christian; Turshatov Andrey; Mailaender Volker; Lorenz Steffen; Baluschev Stanislav^*; Miteva Tzenka; Landfester Katharina

来源：Macromolecular Bioscience, 2011, 11(6): 772-778.

DOI：10.1002/mabi.201000451

• annihilation upconversion
• metallated macrocycles
• miniemulsion polymerization
• nanocapsules

The first energetically conjoined TTA-assisted photon energy upconversion operating in cell tissue is described. The synthesized nanocapsules with the encapsulated UC dye system consisting of an emitter and a sensitizer show very efficient UC emission in aqueous dispersion under extremely low excitation intensity down to 0.05W.cm(-2) so that tissue and cells are not affected by the excitation light. The demonstrated sub-linear intensity dependence of the UC emission is of crucial importance for life-science applications as the UC photon could serve as a local or in situ optical excitation source for subsequent light-triggered processes.

• 出版日期2011-6-14