Antifungal agent and other constituents from Cynanchum otophyllum

作者:Zhao Yi Bin; Shen Yue Mao; He Hong Ping; Mu Quan Zhang; Hao Xiao Jiang*
来源:Natural Product Research, 2007, 21(3): 203-210.
DOI:10.1080/14786410601130364

摘要

Seven constituents were isolated from the ethyl acetate extract of the rhizome of Cynanchum otophyllum Schneid (Asclepiadaceae). Their structures were determined as 1-(4-methoxy-3-(6-methoxy-3-acetylphenylperoxy)phenyl) ethanone (1), 1-(3-hydroxy-7-acetylnaphthalen-2-yl) ethanone (2), 1-(3,4-dihydroxyphenyl) ethanone (3), 1-(2,4-dihydroxyphenyl) ethanone (4), 1-(3-(3,6-dihydroxy-2-methylbenzoyl)-2,4-dihydroxyphenyl) ethanone (beishouwubenzophenone) (5), N,N-dimethylethanamine (6), and 2-oxo-2-phenylacetic acid (7), respectively, by spectral methods. Among them, 1 and 2 were new compounds; 1 had antifungal activity.