Development of a mild and efficient protocol for the protection and O-alkylation of allyl alcohols

作者:Selvakumar Kodirajan*; Lingam Kandapalam Arun Prasath; Varma Rama Varma Luxmi
来源:RSC Advances, 2014, 4(69): 36538-36543.
DOI:10.1039/c4ra06841f

摘要

An efficient, pyridine-free protocol has been developed for the protection of the 3 degrees-allyl alcohol of oxindole using a mild base, such as potassium carbonate, under microwave irradiation conditions. The methodology has been tested with a variety of substrates and protecting group reagents, which provides a clean and good yield of the desired products within a short reaction time.

  • 出版日期2014