Analysis of Herba Asari polysaccharides and their immunological activity

作者：Li, Jingjing; Ji, Li; Sun, Lin; Wei, Ningning; Zhu, Jingjing; Chen, Xiguang; Tai, Guihua^*; Zhou, Yifa

来源：Carbohydrate Polymers, 2012, 87(1): 551-556.

DOI：10.1016/j.carbpol.2011.08.019

• Herbs Asari
• Polysaccharide
• Lymphocyte proliferation

A water-soluble polysaccharide (HA) was extracted from the Herba Asari root. HA was separated into a starch-like glucan fraction (HA1) and a pectin fraction (HA2) using DEAE-cellulose. HA2 was further fractionated into three pectic polysaccharides, HA2-a, HA2-b and HA2-c, using ion-exchange chromatography. NMR and sugar composition analyses demonstrated that HA2-a is an arabinogalactan (AG) and HA2-b and HA2-c are xylogalacturonans (XGA) with AG domains. Lymphocyte proliferation assays showed that both the neutral polysaccharide and acidic polysaccharide were potent B and T cell stimulators that may have two different modes of action.

• 出版日期2012-1-4
• 单位东北师范大学; 中国海洋大学