Direct Regularization From Co-Registered Contrast MRI Improves Image Quality of MRI-Guided Near-Infrared Spectral Tomography of Breast Lesions

作者：Zhang, Limin; Jiang, Shudong; Zhao, Yan; Feng, Jinchao; Pogue, Brian W.; Paulsen, Keith D.^*

来源：IEEE Transactions on Medical Imaging, 2018, 37(5): 1247-1252.

DOI：10.1109/TMI.2018.2794548

• Optical imaging
• breast
• magnetic resonance imaging
• image reconstruction

An approach using direct regularization from co-registered dynamic contrast enhanced magnetic resonance images was used to reconstruct near-infrared spectral tomography patient images, which does not need image segmentation. 20 patients with mammography/ultrasound confirmed breast abnormalities were involved in this paper, and the resulting images indicated that tumor total hemoglobin concentration contrast differentiated malignant from benign cases (p-value = 0.021). The approach produced reconstructed images, which significantly reduced surface artifacts near the source-detector locations (p-value = 4.16e-6).

• 出版日期2018-5
• 单位天津大学; 北京工业大学