Anti-Mullerian hormone levels in American girls by age and race/ethnicity

作者：Elchuri Swati V^*; Patterson Briana C; Brown Milton R; Buchanan Iris; Mertens Ann C; Meacham Lillian R

来源：Journal of Pediatric Endocrinology & Metabolism, 2015, 28(1-2): 189-193.

DOI：10.1515/jpem-2014-0242

• age
• anti-mullerian hormone
• ethnicity
• race

Background: Anti-Mullerian Hormone (AMH), a proposed indicator of ovarian follicle reserve in adults, has not been characterized in pediatric and adolescent females by race and/or ethnicity.
Objectives: To describe AMH levels in healthy American girls and determine the influence of age and race/ethnicity on AMH.
Subjects: Subjects aged 10-21 years were recruited from primary care settings and emergency departments. Race/ethnicity was characterized as White, Black or Hispanic.
Methods: Serum for AMH levels (ng/mL) was measured using an enzyme-linked immunosorbent assay.
Results: Thirty-one White, 60 Black and 24 Hispanic subjects were recruited. Mean AMH levels were 3.19 ng/mL (22.8 pmol/L) (SD 2.12) for Whites, 3.25 ng/mL (23.2 pmol/L) (SD 2.23) for Blacks and 2.97 ng/mL (21.2 pmol/L) (SD 1.75) for Hispanics. ANCOVA showed no difference in AMH levels among race/ethnicities, controlling for age (p=0.91). Age was significantly associated with AMH (p<0.001, R-2=0.12).
Conclusion: AMH levels do not vary by race/ethnicity, and AMH levels increase with age.

• 出版日期2015-1