Multi-layered population structure in Island Southeast Asians

作者：Morseburg Alexander; Pagani Luca; Ricaut Francois Xavier; Yngvadottir Bryndis; Harney Eadaoin; Castillo Cristina; Hoogervorst Tom; Antao Tiago; Kusuma Pradiptajati; Brucato Nicolas; Cardona Alexia; Pierron Denis; Letellier Thierry; Wee Joseph; Abdullah Syafiq; Metspalu Mait; Kivisild Toomas

来源：European Journal of Human Genetics, 2016, 24(11): 1605-1611.

DOI：10.1038/ejhg.2016.60

The history of human settlement in Southeast Asia has been complex and involved several distinct dispersal events. Here, we report the analyses of 1825 individuals from Southeast Asia including new genome-wide genotype data for 146 individuals from three Mainland Southeast Asian (Burmese, Malay and Vietnamese) and four Island Southeast Asian (Dusun, Filipino, Kankanaey and Murut) populations. While confirming the presence of previously recognised major ancestry components in the Southeast Asian population structure, we highlight the Kankanaey Igorots from the highlands of the Philippine Mountain Province as likely the closest living representatives of the source population that may have given rise to the Austronesian expansion. This conclusion rests on independent evidence from various analyses of autosomal data and uniparental markers. Given the extensive presence of trade goods, cultural and linguistic evidence of Indian influence in Southeast Asia starting from 2.5 kya, we also detect traces of a South Asian signature in different populations in the region dating to the last couple of thousand years.

• 出版日期2016-11