Anxiety Levels Are Independently Associated With Cognitive Performance in an Australian Multiple Sclerosis Patient Cohort

作者：Ribbons Karen^*; Lea Rodney; Schofield Peter W; Lechner Scott Jeannette

来源：Journal of Neuropsychiatry and Clinical Neurosciences, 2017, 29(2): 128-134.

DOI：10.1176/appi.neuropsych.16050085

Neurological and psychological symptoms in multiple sclerosis can affect cognitive function. The objective of this study was to explore the relationship between psychological measures and cognitive performance in a patient cohort. In 322 multiple sclerosis patients, psychological symptoms were measured using the Depression Anxiety and Stress Scale, and cognitive function was evaluated using Audio Recorded Cognitive Screen. Multifactor linear regression analysis, accounting for all clinical covariates, found that anxiety was the only psychological measure to remain a significant predictor of cognitive performance (p<0.001), particularly memory p<0.001). Further prospective studies are required to determine whether treatment of anxiety improves cognitive impairment.

• 出版日期2017