ANTIMICROBIAL AND ANALGESIC EVALUATION OF NEWLY SYNTHESIZED BENZOXAZOLE INCORPORATED AZITIDINONES

作者:Hanumanthappa B C; Vagdevi H M*; Vaidya V P; Srikrishna L P; Raghavendra R
来源:Indian Journal of Heterocyclic Chemistry, 2010, 20(2): 121-124.

摘要

The cyclocondensation of the Schiff's bases 5(a-j) with chloroacetyl chloride in presence of triethyl amine resulted in the formation of 2-(1,3-benzoxazole-2-ylthio)-N-(3-chloro-2-oxo-4-phenylazetidin-1-yl) acetamide analogs 6(a-j). The structures of the newly synthesized compounds have been established by IR, (1)H NMR and mass spectral studies. All the synthesized compounds have been screened for antimicrobial and analgesic activities.

  • 出版日期2010-12