The cost-effectiveness of total laparoscopic hysterectomy compared to total abdominal hysterectomy for the treatment of early stage endometrial cancer

作者：Graves Nicholas^*; Janda Monika; Merollini Katharina; Gebski Val; Obermair Andreas

来源：BMJ Open, 2013, 3(4): e001884.

DOI：10.1136/bmjopen-2012-001884

• Health economics

Objective To summarise how costs and health benefits will change with the adoption of total laparoscopic hysterectomy compared to total abdominal hysterectomy for the treatment of early stage endometrial cancer. %26lt;br%26gt;Design Cost-effectiveness modelling using the information from a randomised controlled trial. %26lt;br%26gt;Participants Two hypothetical modelled cohorts of 1000 individuals undergoing total laparoscopic hysterectomy and total abdominal hysterectomy. %26lt;br%26gt;Outcome measures Surgery costs; hospital bed days used; total healthcare costs; quality-adjusted life years; and net monetary benefits. %26lt;br%26gt;Results For 1000 individuals receiving total laparoscopic hysterectomy surgery, the costs were $509575 higher, 3548 hospital fewer bed days were used and total health services costs were reduced by $3746221. There were 39.13 more quality-adjusted life years for a 5year period following surgery. %26lt;br%26gt;Conclusions The adoption of total laparoscopic hysterectomy is almost certainly a good decision for health services policy makers. There is 100% probability that it will be cost saving to health services, a 86.8% probability that it will increase health benefits and a 99.5% chance that it returns net monetary benefits greater than zero.

• 出版日期2013