Advancement of Mesenchymal Stem Cell Therapy in Solid Organ Transplantation (MISOT)

作者：Hoogduijn Martin J^*; Popp Felix C; Grohnert Anja; Crop Meindert J; van Rhijn Marieke; Rowshani Ajda T; Eggenhofer Elke; Renner Philipp; Reinders Marlies E; Rabelink Ton J; van der Laan Luc J W; Dor Frank J M F; IJzermans Jan N M; Genever Paul G; Lange Claudia; Durrbach Antoine; Houtgraaf Jaco H; Christ Bruno; Seifert Martina; Shagidulin Murat; Donckier Vincent; Deans Robert; Ringden Olle; Perico Norberto; Remuzzi Giuseppe; Bartholomew Amelia

来源：Transplantation, 2010, 90(2): 124-126.

DOI：10.1097/TP.0b013e3181ea4240

• Mesenchymal stem cell
• Solid organ transplantation
• Clinical trial
• MISOT

There is evolving interest in the use of mesenchymal stem cells (MSC) in solid organ transplantation. Pre-clinical transplantation models show efficacy of MSC in prolonging graft survival and a number of clinical studies are planned or underway. At a recent meeting of the MISOT consortium (MSC In Solid Organ Transplantation) the advances of these studies were evaluated and mechanisms underlying the potential effects of MSC discussed. Continued discussion is required for definition of safety and eventually efficacy endpoints for MSC therapy in solid organ transplantation.

• 出版日期2010-7-27
• 单位河北医科大学