Anti-Inflammatory and Analgesic Activities of the Complex of Flavonoids from Lychnis chalcedonica L.

Nesterova Yu V<sup>*</sup>; Povet'eva T N; Zibareva L N; Suslov N I; Zueva E P; Aksinenko S G; Afanas'eva O G; Krylova S G; Amosova E N; Rybalkina O Yu; Lopatina K A

doi:10.1007/s10517-017-3771-5

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Anti-Inflammatory and Analgesic Activities of the Complex of Flavonoids from Lychnis chalcedonica L.

作者：Nesterova Yu V^*; Povet'eva T N; Zibareva L N; Suslov N I; Zueva E P; Aksinenko S G; Afanas'eva O G; Krylova S G; Amosova E N; Rybalkina O Yu; Lopatina K A

来源：Bulletin of Experimental Biology and Medicine, 2017, 163(2): 222-225.

DOI：10.1007/s10517-017-3771-5

摘要

Anti-inflammatory and analgesic activities of the complex of flavonoids from Lychnis chalcedonica L.were studied in the models of acute aseptic inflammation induced by carrageenan, histamine, and serotonin and acetic acid- induced painful chemical stimulation. It is demonstrated that course treatment with flavonoids derived from Lychnis chalcedonica L. produced a stable pharmacological effect comparable with that of the reference anti-inflammatory drug diclofenac.