Affinity measured by microcluster

作者:Fooksman David R; Dustin Michael L*
来源:Journal of Experimental Medicine, 2010, 207(5): 907-909.
DOI:10.1084/jem.20100780

摘要

Like T cell activation, B cell activation is driven by aggregation of B cell receptors (BCRs) into microclusters. New work suggests that the early dynamics of BCR mobility and microcluster formation "translate" BCR affinity for antigen into B cell responsiveness.

  • 出版日期2010-5-10