A single aldehyde group can serve as a structural element for recognition by transmembrane protein CD36

作者：Tsuzuki Satoshi^*; Amitsuka Takahiko; Okahashi Tatsuya; Kozai Yuki; Matsumura Shigenobu; Inoue Kazuo; Fushiki Tohru

来源：Bioscience Biotechnology and Biochemistry, 2016, 80(7): 1375-1378.

DOI：10.1080/09168451.2016.1151343

• aldehyde functional group
• CD36 ligands
• fatty acid-related molecules
• oleic aldehyde
• receptor-binding moiety

Transmembrane protein CD36 is considered to bind its distinct ligands such as long-chain fatty acids primarily by recognizing their terminal carboxyl moiety. In this study, we provide evidence that long-chain fatty aldehydes, such as oleic aldehyde, can be recognized by CD36. We suggest that a single aldehyde group may also serve as one of the structural elements recognizable by CD36.

• 出版日期2016-7