Antiwrinkle effect of topical adhesive pads on crow's feet: How long does the effect last for?

作者：Mazzarello Vittorio^*; Ferrari Marco; Bulla Antonio; Piu Gabriella; Montella Andrea

来源：Journal of Cosmetic Dermatology, 2018, 17(3): 484-490.

DOI：10.1111/jocd.12395

• anti-aging
• cosmetic dermatology
• noninvasive
• skin treatment
• wrinkles

BackgroundAdhesive pads should reduce the action of the local muscle contraction on the skin leading to a decrease in the depth of existing wrinkles and the formation of new dynamic wrinkles.
Aim of the workThis study aims at assessing the antiwrinkles action of adhesive pads during time, and the temporary improvement of facial skin appearance by reducing the vision of linear wrinkles and improving skin elasticity.
Patients and methodsThirty-nine subjects participated to a placebo-controlled study. In the short-term test, the measurements were taken 15, 30, and 60minutes following 30minutes application of the product; in the long-term test, the measurements were taken after wearing pads every night for 4weeks. The roughness parameter of the skin surface was calculated by using a profilometry software 3D MEX (R).
ResultsIn the short- and long-term tests, analyzing the average of the elastomeric measurements, no significant change was observed in any of the parameters analyzed after 15, 30, and 60minutes. The adhesive pad decreased significantly all roughness skin parameters 15minutes after short-term application and until 60minutes after long-term application. These changes did not occur in the contralateral untreated zone.
ConclusionsThe use of topical adhesive pads improves wrinkles in the crow's feet area in the first hour after use. However, patient self-evaluation indicated that the use of topical adhesive pads for 3weeks may offer subjective improvement in crow's feet zone over a 2hour period. Topical adhesive pads are safe to use and tolerable for most users.

• 出版日期2018-6