科研之友
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摘要
The room temperature radical decarboxylative allylation of N-protected alpha-amino acids and esters has been accomplished via a combination of palladium and photoredox catalysis to provide homoallylic amines. Mechanistic investigations revealed that the stability of the alpha-amino radical, which is formed by decarboxylation, dictates the predominant reaction pathway between competing mechanisms.
- 出版日期2015-12-14
