Antioxidant and cytotoxic properties of an aqueous extract from the Argentinean plant Hedeoma multiflorum

作者：Miguel Dade Martin; Raul Schinella Guillermo; Emilio Fioravanti Daniel; AlfioTournier Horacio^*

来源：Pharmaceutical Biology, 2011, 49(6): 633-639.

DOI：10.3109/13880209.2010.526949

• Hedeoma multiflorum
• scavenger
• lipid peroxidation
• apoptosis
• polymorphonuclear neutrophils

Context: Hedeoma multiflorum Benth. (Lamiaceae) is widely used in Argentinean popular medicine for digestive and anti-spasmodic purposes. However, knowledge about its pharmacological properties has been poorly investigated.
Objective: The antioxidant and cytotoxic properties of an aqueous extract from the plant were investigated for the first time.
Material and methods: Scavenging of stable free radicals of 2,2-azino-bis (3-ethylbenzo-thiazoline-6-sulfonic acid) diammonium salt (ABTSResults: Extract scavenged ABTSDiscussion and conclusion: H. multiflorum extract was found to have a significant antioxidant and pro-apoptotic activities, and a great potential as a source of healthy products.

• 出版日期2011-6