Embryo banking between induction and consolidation chemotherapy in women with leukemia

作者：Rossi Brooke V^*; Ashby Rachel K; Srouji Serene S

来源：Fertility and Sterility, 2011, 96(6): 1412-1414.

DOI：10.1016/j.fertnstert.2011.09.038

• Fertility preservation
• leukemia
• chemotherapy
• cancer

Objective: To report the results of controlled ovarian hyperstimulation (COH) after long-acting GnRH agonist (GnRH-a) and chemotherapy for the purposes of embryo cryopreservation.
Design: Case report.
Setting: University medical center.
Patient(s): Two premenopausal women with acute myelogenous leukemia with recent treatment with GnRH-a and induction chemotherapy for hematopoietic cell transplantation (HCT).
Intervention(s): COH with embryo cryopreservation.
Main Outcome Measure(s): Numbers of oocytes and embryos cryopreserved.
Result(s): Both patients responded to gonadotropin stimulation and cryopreserved embryos.
Conclusion(s): Women who have received recent long-acting GnRH-a and chemotherapy may respond to gonadotropin stimulation. The option of embryo banking can be offered to leukemia patients who are preparing for HCT. (Fertil Steril (R) 2011; 96: 1412-4.

• 出版日期2011-12