APPLICATION OF A NOVEL MICROVASCULAR IMAGING TECHNIQUE IN BREAST LESION EVALUATION

作者:Zhao Yongfeng; Zhou Ping*; Liu Wengang; Shao Yang; Tian Shuangming
来源:Ultrasound in Medicine and Biology, 2016, 42(9): 2097-2105.
DOI:10.1016/j.ultrasmedbio.2016.05.010

摘要

Conventional power Doppler imaging (PDI) and the novel Superb Microvascular Imaging (SMI) technique were applied to observe the distribution of microvessels in 135 breast lesions, using semi-quantitative grading, penetrating vessel evaluation and flow distribution pattern to evaluate diagnostic efficacy. Compared with PDI, SMI detected more flow signals and details of microvessels. Further, when a centrally distributed branching or diffusing mode was used as a criterion for diagnosing malignancy, SMI improved diagnosis of breast masses. Sensitivity, specificity, positive predictive value and negative predictive value of SMI-assessed flow distribution were 85.4%, 92.6%, 83.3% and 93.5%, respectively, compared with 70.7%, 92.6%, 80.5% and 87.9% for PDI. We also found that flow distribution pattern analysis is superior to semi-quantitative grading and the penetrating vessel method in differentiating malignant breast lesions. Our work here further supports SMI as a novel and promising technique in visualizing microvasculature in breast lesions that may be of paramount use in initial diagnosis as well as follow-up assessment in various treatment regimes. (E-mail: zhouping1000@ hotmail.