Aluminium dodecyl sulfate trihydrate [Al(DS)3]center dot 3H(2)O: An efficient Lewis acid-surfactant-combined catalyst for synthesis of 1,8-dioxo-octahydroxanthens and 1,8-dioxo-decahydroacridines

作者：Hasaninejad A; Yousefy T; Firoozi S^*

来源：Iranian Journal of Science and Technology Transaction A-Science, 2015, 39(A2): 129-140.

• Aluminium dodecyl sulfate trihydrate
• Lewis acid
• Lewis acid surfactant catalyst
• Xanthenes
• 1,8-Dioxo-octahydroxanthens
• Acridinediones
• 1,8-Dioxo-decahydroacridines
• multi component reactions
• green chemistry

An efficient synthesis of 1, 8-dioxo-octahydroxanthens and 1, 8-dioxo-decahydroacridines from the reaction of 5,5-dimethy1-1,3-cyclohexanedione (dimedone) with aromatic aldehydes bearing electron -donating or withdrawing substituents either in the presence or absence of primary amines has been described in a single pot using a catalytic amounts of aluminum tris (dodecyl sulfate) trihydrate [Al(DS)3.3H(2)O] as a Lewis acid -surfactant combined catalyst. Both reactions occurred at 80 degrees C. 1, 8-dioxo-octahydroxanthens has been synthesized under solvent -free conditions and water is used as a green solvent for the synthesis of 1, 8-dioxo-decahydroacridines. This methodology offers several advantages such as very simple work -up procedure, short reaction times, and mild reaction conditions.

• 出版日期2015