An Efficient Protocol for the Synthesis of 2-Phenylquinazolines Catalyzed by Ceric Ammonium Nitrate (CAN)

作者：Karnakar K; Shankar J; Murthy S Narayana; Ramesh K; Nageswar Y V D^*

来源：Synlett, 2011, 2011(8): 1089-1096.

DOI：10.1055/s-0030-1259960

• 2-aminobenzophenones
• benzylamines
• ceric ammonium nitrate
• tert-butyl hydroperoxide
• acetonitrile

A facile and efficient method for the synthesis of 2-phenylquinazolines has been developed from 2-aminobenzophenones and benzylamines catalyzed by ceric ammonium nitrate (CAN)-TBHP in acetonitrile. The corresponding 2-phenylquinazolines were obtained in good to excellent yields.

• 出版日期2011-5