Nanomedicines Targeting the Tumor Microenvironment

作者：Tong Rong; Langer Robert^*

来源：Cancer Journal, 2015, 21(4): 314-321.

DOI：10.1097/PPO.0000000000000123

• Cancer immunology
• extracellular matrix
• nanomedicine
• nanoparticle
• near-infrared light
• photothermal
• stimulus-responsive drug delivery
• triggered drug delivery
• tumor microenvironment
• tumor penetration

We review recent progress in cancer nanomedicine to overcome the delivery barriers in tumor microenvironment, including the understanding in the nanomedicine delivery process, stimulus-responsive delivery, and several new strategies to normalize tumor microenvironment. The application of nanomedicine in cancer immunotherapy, a renewed cancer therapy by recent breakthrough, is also highlighted.

• 出版日期2015-8
• 单位MIT