Adsorption kinetics of hemoglobin onto silicate adsorbents

作者：Atyaksheva L F^*; Chukhrai E S; Ivanova I I; Knyazeva E E; Ovsyannikov R A

来源：Russian Journal of Physical Chemistry, 2010, 84(6): 1071-1075.

DOI：10.1134/S0036024410060324

A comparative study was performed of the adsorption kinetics of hemoglobin onto four silicate adsorbents that differed in parameters of porous structure: industrial silochrome, and three silicates obtained by template synthesis. The existence of a reversible stage of the process preceding irreversible protein binding was shown by kinetic analysis. Rate constants for the reversible stage of the process and the effective constants of first order rate were calculated. It was concluded that the adsorption rate is the highest on silochrome and the lowest on silicate of MCM-41 type, the pore size of which is comparable to the diameter of a hemoglobin molecule. The constant of the desorption rate for the first reversible stage of the process was shown in the case of mesoporous silicates to be lower by a factor of 3.5-4 than in the case of silochrome.

• 出版日期2010-6