Lamellar Macular Holes Associated with End-Stage Exudative Age-Related Macular Degeneration

作者：Segal Ori^*; Ferencz Joseph R; Mimouni Michael; Nesher Ronit; Cohen Perri; Nemet Arie Y

来源：Israel Medical Association Journal, 2015, 17(12): 750-754.

• age-related macular degeneration (AMD)
• end-stage AMD
• lamellar macular hole (LMH)
• optical coherence tomography (OCT)

Background: Reports of lamellar macular holes (LMHs) with underlying age-related macular degeneration (AMD) are rare, and the specific definition, pathogenesis and surgical recommendations for this macular condition remain unclear. Objectives: To present a series of LMHs in eyes with underlying end-stage AMD, and describe optical coherence tomography (OCT) detection of associated morphologic abnormalities.
Methods: We reviewed the files of consecutive patients diagnosed with LMH and underlying end-stage AMD between September 2007 and September 2011.
Results: Sixteen eyes of 14 patients were included in this study. The average follow-up after the OCT-established diagnosis of LMH was 19.8 months (range 4-48). The average visual acuity (VA) at last follow-up visit was 20/400 (20/60-20/1200). The best-corrected VA was stable in 10 eyes (62.5%) and deteriorated in 6(37.5%). There was a statistically significant correlation between VA and minimal foveal thickness (r=-0.598, P=0.014).
Conclusions: In this series of LMHs with underlying AMD the OCT findings were intraretinal fluid, cystic spaces and window defect.

• 出版日期2015-12