An Efficient Copper-Catalyzed Homocoupling of Terminal Alkynes to Give Symmetrical 1,4-Disubstituted 1,3-Diynes

作者：Zhang, Songlin^*; Liu, Xiaoyan; Wang, Tongqiang

来源：Advanced Synthesis & Catalysis, 2011, 353(9): 1463-1466.

DOI：10.1002/adsc.201100035

• ambient temperature process
• catalysis
• copper
• 1,3-diynes
• N,N,N ',N '-tetramethylethane-1,2-diamine

A facile and efficient pathway for the copper iodide and ligand N,N,N',N'-tetramethylethane-1,2-diamine promoted homocoupling reaction of terminal alkynes under ambient temperature and air as an oxidant was reported. The alkynes, including aromatic alkynes and aliphatic alkynes, could afford the symmetrical 1,4-disubstituted 1,3-diynes in good to excellent yields.

• 出版日期2011-6
• 单位苏州大学