A Multicenter Study on Optimizing Piperacillin-Tazobactam Use: Lessons on Why Interventions Fail

作者：Gaynes Robert P^*; Gould Carolyn V; Edwards Jonathan; Antoine Theresa L; Blumberg Henry M; DeSilva Kathryn; King Mark; Kraman Alice; Pack Jan; Ribner Bruce; Seybold Ulrich; Steinberg James; Jernigan John A

来源：Infection Control and Hospital Epidemiology, 2009, 30(8): 794-796.

DOI：10.1086/599002

We examined interventions to optimize piperacillin-tazobactam use at 4 hospitals. Interventions for rotating house staff did not affect use. We could target empiric therapy in only 35% of cases. Because prescribing practices seemed to be institution specific, interventions should address attitudes of local prescribers. Interventions should target empiric therapy and ordering of appropriate cultures.

• 出版日期2009-8