25-hydroxy-vitamin D demography and the risk of vitamin D insufficiency in the South East Asian Nutrition Surveys (SEANUTS)

作者：Poh Bee Koon; Rojroongwasinkul Nipa; Bao Khanh Le Nguyen; Sandjaja; Ruzita Abd Talib; Yamborisut Uruwan; Truong Nguyen Hong; Ernawati Fitrah; Deurenberg Paul; Parikh Panam^*

来源：Asia Pacific Journal of Clinical Nutrition, 2016, 25(3): 538-548.

DOI：10.6133/apjcn.092015.02

• vitamin D
• 25(OH)D
• children
• SEANUTS
• aetiology

The South East Asian Nutrition Surveys (SEANUTS) were conducted in 2010/2011 in Indonesia, Malaysia, Thailand and Vietnam in country representative samples totalling 16,744 children aged 0.5 to 12 years. Information on socio-demographic and behavioural variables was collected using questionnaires and anthropometric variables were measured. In a sub-sample of 2016 children, serum 25-hydroxy-vitamin D (25(OH) D) was determined. Data were analysed using SPSS complex sample with weight factors to report population representative data. Children were categorized as deficient (<25 nmol/L), insufficient (<50 nmol/L), inadequate (<75 nmol/L) or desirable (>= 75 nmol/L). In Malaysia and Thailand, urban children had lower 25(OH) D than rural children. In all countries, except Vietnam, boys had higher 25(OH) D levels and older children had lower 25(OH) D. Regional differences after correcting for age, sex and area of residence were seen in all countries. In Thailand and Malaysia, 25(OH) D status was associated with religion. The percentage of children with adequate 25(OH) D (>= 75 nmol/L) ranged from as low as 5% (Indonesia) to 20% (Vietnam). Vitamin D insufficiency (<50 nmol/L) was noted in 40 to 50% of children in all countries. Logistic regression showed that girls, urban area, region within the country and religion significantly increased the odds for being vitamin D insufficient. The high prevalence of vitamin D insufficiency in the (sub) tropical SEANUTS countries suggests a need for tailored approach to successfully combat this problem. Promoting active outdoor livestyle with safe sunlight exposure along with food-based strategies to improve vitamin D intake can be feasible options.

• 出版日期2016-9