NMR assignment of the domain 513-651 from the SARS-CoV nonstructural protein nsp3

作者：Chatterjee Amarnath; Johnson Margaret A; Serrano Pedro; Pedrini Bill; Wuthrich Kurt^*

来源：Biomolecular NMR Assignments, 2007, 1(2): 191-194.

DOI：10.1007/s12104-007-9052-x

• SARS-CoV
• nonstructural protein
• nsp3
• nsp3c
• SARS-unique domain

Sequence-specific NMR assignments of an internal domain of the protein nsp3, nsp3(513-651), which is a part of the SARS coronavirus (SARS-CoV) replicase polyprotein, have been determined, using triple-resonance NMR experiments with the uniformly [(13)C, (15)N]-labeled protein. The complete assignments (>99%) provide the basis for the ongoing three-dimensional structure determination.

• 出版日期2007-12