Aggregation Behavior of Poly(ethylene glycol)-block-poly (gamma-benzyl L-glutamate)-graft-poly(ethylene glycol) Copolymer and its Blends with Poly(gamma-benzyl L-glutamate) Homopolymer in Mixed Solvents

作者：Zhu Guoquan^*; Wang Fagang; Ding Zhen; Liu Yuying; Gao Qiaochun

来源：Journal of Macromolecular Science Part A-Pure and Applied Chemistry, 2010, 47(10): 1006-1011.

DOI：10.1080/10601325.2010.507991

• Aggregation behavior
• PEG-b-PBLG-g-PEG
• blends
• mixed solvents

Poly(ethylene glycol)-block-poly(-benzyl L-glutamate)-graft-poly(ethylene glycol) (PEG-b-PBLG-g-PEG) copolymer was synthesized by the ester exchange reaction of PBLG-block-PEG copolymer with mPEG. The self-association behaviors of PEG-b-PBLG-g-PEG and its blends with PBLG homopolymer in the mixtures of ethanol and dimethylformamide (DMF) were investigated by transmission electron microscopy (TEM), dynamic light scattering (DLS), and viscometry. Effects of the introduction of PBLG homopolymer, the grafting ratio, and the DMF content on the self-association behaviors of PEG-b-PBLG-g-PEG copolymer in the mixtures of ethanol and DMF were mainly researched. It was revealed that PEG-b-PBLG-g-PEG copolymer could self-assemble to form polymeric micelles with a core-shell structure in various shapes from different preparation conditions. The critical micelle concentration (CMC) and the average particle diameter of the micelles formed by PEG-b-PBLG-g-PEG copolymer in the mixed solvents also changed with different preparation conditions.

• 出版日期2010
• 单位山东理工大学