A Peptide Produced by Pseudomonas tolaasi, Tolaasin Binds to Metal Ions

作者:Lee Sunhee; Jo Geunhyeong; Hwang Doseok; Woo Yoonkyung; Lee Younggiu; Yong Yeonjoong; Kang Kyungrai; Hyun Jiye; Kim Young Kee; Kim Dong Woon; Lim Yoongho*
来源:Journal of the Korean Society for Applied Biological Chemistry, 2011, 54(4): 633-636.
DOI:10.3839/jksabc.2011.096

摘要

Brown blotch disease in mushrooms is caused by Pseudomonas tolaasin, which produces a peptide toxin, tolaasin 1, and zinc ion inhibits the channel formed by tolaasin I. NMR experiments revealed that zinc, sodium, and calcium ions can bind to tolaasin 1 and their binding position on tolaasin I is the lactone ring.

  • 出版日期2011-8