An efficient copper-catalytic system for performing intramolecular O-arylation reactions in aqueous media. New synthesis of xanthones

作者：Barbero Nekane^*; SanMartin Raul; Dominguez Esther

来源：Green Chemistry, 2009, 11(6): 830-836.

DOI：10.1039/b900931k

A safe, efficient protocol for the copper-catalysed intramolecular O-arylation of 2-halobenzophenones on water to afford the valuable xanthone framework is reported. The recovery and the successful reutilization of the aqueous solution containing the copper catalyst are also presented. Moreover, the scalability and the easy setup and purification tasks of this sustainable method make it appealing for bulk industry applications.

• 出版日期2009