ANTILISTERIAL POTENTIAL OF IMPERATORIN AND LIMONIN FROM PONCIRUS TRIFOLIATA RAFIN

作者:Rahman Atiqur; Na Minkyun; Kang Sun Chul*
来源:Journal of Food Biochemistry, 2012, 36(2): 217-223.
DOI:10.1111/j.1745-4514.2010.00528.x

摘要

To discover natural compounds with antilisterial potential, we investigated an ethyl acetate extract of the seeds of Poncirus trifoliata Rafin., and isolated imperatorin and limonin. The structures were determined on the basis of spectroscopic analysis. The compounds were tested for antibacterial activity against some Listeria monocytogenes strains and found to possess potential antilisterial activity against L. monocytogenes American Type Culture Collection (ATCC 19116, 19111, 19166, 19118 and 15313) with minimum inhibitory concentration (MIC) values ranging from 15.62 to 62.5 mu g/mL. The scanning electron microscopic studies also demonstrated that imperatorin and limonin caused morphological changes of L. monocytogenes ATCC 19116 at the MIC value, along with the potential effect on cell viabilities of the tested bacteria.

  • 出版日期2012-4