Antihypertensive therapy in diabetes mellitus - Guidelines of the Austrian Diabetes Association 2016

作者：Schernthaner Guntram; Drexel Heinz; Rosenkranz Alexander; Schernthaner Gerit Holger; Watschinger Bruno

来源：WIENER KLINISCHE WOCHENSCHRIFT, 2016, 128(S2): S62-S67.

DOI：10.1007/s00508-015-0924-2

• Diabetes mellitus
• Blood pressure lowering
• Antihypertensive therapy
• Myocardial infarction
• Stroke
• Peripheral arterial disease
• Diabetic nephropathy

Blood pressure lowering is one of the most important interventions for reducing the vascular complications and mortality in patients with diabetes mellitus. Recent studies indicate that the optimal blood pressure level might be in the range between 130-140 mmHg systolic and 80-90 mmHg diastolic. Lower blood pressure levels (e.g. 120/80 mmHg) can further reduce the risk for stroke and diabetic nephropathy, but are associated with increased cardiovascular mortality. In particular, very low blood pressure levels (< 120 mmHg) should be avoided in patients with coronary heart disease or peripheral arterial disease. Most patients with diabetes mellitus need antihypertensive combination therapies, whereby ACE-inhibitors or Angiotensin-II receptor antagonists should be first line drugs.

• 出版日期2016-4