A Case of Type 2 Diabetes and Metastatic Liver Cancer Exhibiting Hypercholesterolemia with Abnormal Lipoproteins

作者:Kanzaki Motoko; Wada Jun*; Nakatsuka Atsuko; Teshigawara Sanae; Murakami Kazutoshi; Inoue Kentaro; Terami Takahiro; Katayama Akihiro; Nasu Junichiro; Yamamoto Kazuhide; Makino Hirofumi
来源:Internal Medicine, 2012, 51(6): 619-623.
DOI:10.2169/internalmedicine.51.6486

摘要

Although the appearance of abnormal lipoproteins in liver diseases is well known, the precise analyses of abnormal lipoproteins remain elusive. Here, we report a 71-year-old woman with type 2 diabetes whose serum cholesterol levels were elevated to 560 mg/dL over a 4-month period. High-performance liquid chromatography demonstrated the presence of lipoprotein-X and lipoprotein-Y and sigmoid colon cancer and multiple liver metastases were found by colonoscopy and computed tomography. Remission of the primary colon cancer and liver lesions was achieved by chemotherapy with oxaliplatin and fluorouracil and her serum cholesterol went back to basal levels associated with the disappearance of abnormal lipoproteins.

  • 出版日期2012

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