A New Daphne Diterpenoids from Daphne acutiloba Rehd.

作者:Xu, Yi-Ran*; Li, Yin-Ke; Cao, Jing-Li; Zhang, Xin; Yang, Guang-Yu; Hu, Qiu-Fen
来源:Asian Journal of Chemistry, 2010, 22(8): 6371-6374.

摘要

A new daphne diterpenoid (daphnediterp A) was isolated from the leaf and steam of Daphne acutiloba Rehd. Its structure was determined by means of HRESIMS, extensive D-1 and D-2 NMR spectroscopic studies and chemical evidence. The anti HIV-1 activity was also evaluated and it shows an anti HIV-1 activity with a therapeutic index above 31.4.