NUCLEOTIDE-SEQUENCES OF NORMAL AND REARRANGED RNA SEGMENTS-10 OF HUMAN ROTAVIRUSES

作者:BALLARD A; MCCRAE MA; DESSELBERGER U
来源:Journal of General Virology, 1992, 73: 633-638.
DOI:10.1099/0022-1317-73-3-633

摘要

Normal and rearranged RNA segments 10 of group A rotaviruses isolated from a chronically infected immunodeficient child were amplified by the polymerase chain reaction as full-length cDNA copies, and were subsequently cloned and sequenced. Compared with the nucleotide sequence of the normal RNA segment 10, the rearranged form contains a partial non-coding duplication at its 3' end and several point mutations. The normal RNA segment 10 was similar to that of bovine rotavirus.

  • 出版日期1992-3

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