Addition of secondary phosphines to N-vinylpyrroles

作者：Trofimov BA; Malysheva SF^*; Sukhov BG; Belogorlova NA; Schmidt EY; Sobenina LN; Kuimov VA; Gusarova NK

来源：Tetrahedron Letters, 2003, 44(13): 2629-2632.

DOI：10.1016/S0040-4039(03)00382-4

• secondary phosphines
• N-vinylpyrroles
• addition
• radical initiation
• functional tertiary phosphines

Secondary phosphines 1-3 react readily with N-vinylpyrroles 4 and 5 under radical initiation to give regiospecifically anti-Markovnikov adducts, diorganyl-2-(1-pyrrolyl)ethylphosphilies 6a-d, highly reactive building blocks for organic synthesis, in 88-91% yields.

• 出版日期2003-3-24