Birth defects after assisted reproductive technologies in China: analysis of 15,405 offspring in seven centers (2004 to 2008)

作者：Yan, Junhao; Huang, Guoning; Sun, Yingpu; Zhao, Xiaoming; Chen, Shiling; Zou, Shuhua; Hao, Cuifang; Quan, Song; Chen, Zi-Jiang^*

来源：Fertility and Sterility, 2011, 95(1): 458-460.

DOI：10.1016/j.fertnstert.2010.08.024

• Birth defects
• assisted reproductive technology (ART)
• in vitro fertilization (IVF)
• intracytoplasmic sperm injection (ICSI)
• cryopreserved embryo transfer (CET)
• artificial insemination donor (AID)
• artificial insemination husband (AIH)

This first large-scale report of birth defects in 15,405 offspring conceived by assisted reproductive technologies in China found infants born after IVF alone to have a birth defect frequency comparable to that in the general Chinese population; rates were nonsignificantly higher in infants conceived with use of intracytoplasmic sperm injection compared with those conceived after IVF alone. (Fertil Steril (R) 2011;95:458-60.

• 出版日期2011-1
• 单位郑州大学; 烟台毓璜顶医院; 山东大学; 南方医科大学