科研之友
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摘要
We report here the highly stable niosomes (non-ionic vesicles) from 1:1 Tween-80/Triton X-100 mixed surfactants in presence of n-octanol as an organic additive. Niosomes of nanometer dimensions resulted at a total surfactant concentration ranging from 0.1 - 1 wt%. The critical concentration of the additive, n-octanol used to form niosomes was found to be 15 mM. The unilamellar vesicles thus formed had a mean diameter of similar to 100 nm for 0.1 wt% and similar to 300 nm for 1 wt% concentration. Phase evolution in the mixed 1:1 Tween-80/Triton X-100 surfactant system was unraveled upon investigating the morphology, based on microscopic and dynamic light scattering investigations. The formed vesicles are envisaged as probable potential drug carriers.
- 出版日期2013
