A New Approach to 3-Substituted Indoles through Palladium-Catalyzed C-H Activation Followed by Intramolecular Amination Reaction of Enamines

作者：Inamoto Kiyofumi^*; Saito Tadataka; Hiroya Kou; Doi Takayuki

来源：Synlett, 2008, 2008(20): 3157-3162.

DOI：10.1055/s-0028-1087413

• palladium
• catalysis
• C-H activation
• indoles
• aminations

Palladium-catalyzed C-H activation followed by intramolecular amination reaction of enamine compounds was achieved using a Pd(OAc)(2) (10 mol%)/Cu(OAc)(2) (100 mol%) catalyst system in DMSO. This work introduces an entirely new approach to 3-substituted indoles.

• 出版日期2008-12-16