科研之友
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摘要
Introduction: Non-invasive peripheral pulse oximeters are routinely used to measure oxyhaemoglobin saturation (SpO(2)) in cyanotic congenital heart disease. These probes are calibrated in healthy adult volunteers between arterial saturations of similar to 75 and 100%, using the gold standard of co-oximetry on arterial blood samples. There are little data to attest their accuracy in cyanotic congenital heart disease. Aims: We aimed to assess the accuracy of a commonly used probe in children with cyanotic congenital heart disease. Methods: Children with cyanotic congenital heart disease admitted to the Paediatric Intensive Care Unit with an arterial line in situ were included to our study. Prospective simultaneous recordings of SpO(2), measured by the Masimo SET (R) LNCS Neo peripheral probe, and co-oximeter saturations (SaO(2)) measured by arterial blood gas analysis were recorded. Results: A total of 527 paired measurements of SpO(2) and SaO(2) (using an ABL800 FLEX analyser) in 25 children were obtained. The mean bias of the pulse oximeter for all SaO(2) readings was +4.713.8%. The wide standard deviation indicates poor precision. This mean bias increased to +7.0 +/- 13.7% at SaO(2) recordings <75%. The accuracy root mean square of the recordings was 3.30% across all saturation levels, and this increased to 4.98% at SaO(2) <75%. Conclusions: The performance of the Masimo SET (R) LNCS Neo pulse oximeter is poor when arterial oxyhaemoglobin saturations are below 75%. It tends to overestimate saturations in children with cyanotic congenital heart disease. This may have serious implications for clinical decisions.
- 出版日期2016-8
