An Alternative Method for Predicting the Risk of Postoperative Complications in Lung Resection

作者：Vargas Fajardo Maria del Carmen; Novoa Valentin Nuria Maria; Jimenez Lopez Marcelo Fernando; Ramos Gonzalez Jacinto; Varela Simo Gonzalo

来源：Archivos de Bronconeumologia, 2014, 50(3): 87-92.

DOI：10.1016/j.arbres.2013.09.010

• Pedometer
• Oxygen consumption
• VO2
• Surgical risk
• Lung resection
• Postoperative complications

Objectives: The aims of this study were to design a best fit linear regression model to estimate VO(2)max, (estimated VO2) and to compare the ability of VO2 values (measured and estimated) predicting cardiorespiratory complications in a series of patients undergoing lung resection for lung cancer. %26lt;br%26gt;Method: This was a prospective, observational study performed in 83 patients. Variables analyzed were: demographic characteristics, comorbidity, body mass index (BMI), FEV1%, FVC%, diffusion capacity (DLCO%), mean daily distance walked in kilometers, VO2max measured by cardio-pulmonary exercise test (CPET) and postoperative complications. Descriptive and comparative statistical analysis of the variables was performed using the Mann-Whitney test for categorical variables and the Student%26apos;s t-test for continuous variables. A new linear regression model was designed, where the dependent variable (measured VO2max) was estimated by the distance, DLCO% and age, resulting in the estimated VO2. The predictive power of the measured and estimated consumption was analyzed using the Student%26apos;s t-test, grouping by the occurrence or absence of cardiorespiratory complications. %26lt;br%26gt;Results: Both groups were homogeneous for age, sex, BMI, FEV1%, DLCO%, comorbidity, type of resection performed and mean distance walked per day. Estimated VO2 and measured VO2 were normally distributed (K-Smirnov test, P%26gt;.32). VO2 means estimated by the model (age, DLCO% and mean distance walked per day) were significantly different between patients with and without complications (Student%26apos;s t test, P=.037) compared with measured VO2 values, which did not differentiate groups (Student%26apos;s t test, P=.42). %26lt;br%26gt;Conclusion: The VO2max estimated by the model is more predictive in this case series than the VO2max measured during a standard exercise test.

• 出版日期2014-3