An Unusual Type of Kidney Stone

作者:De Koninck Anne Sophie; Groen Luitzen Albert; Maes Heleen; Verstraete Alain Gaston; Stove Veronique; Delanghe Joris Richard*
来源:Clinical Laboratory, 2016, 62(1-2): 235-239.
DOI:10.7754/Clin.Lab.2015.150605

摘要

A very rare case of acetylsulfapyridine nephrolithiasis is presented in a 54-year old female patient who had been prescribed sulfasalazine (6 x 500 mg/day) because of psoriatic arthritis for the last 9 years. The patient's renal function was only slightly impaired. Reflectance infrared spectroscopy and gas chromatography-mass spectrometry allowed the identification of the chemical nature of the stone. As acetylsulfapyridine is a metabolite of sulfasalazine, administration of the latter drug was the cause of the nephrolithiasis.

  • 出版日期2016