科研之友
微信
新浪微博
Facebook
分享链接
摘要
A mild, convenient, and efficient one-pot synthesis of amino-1,3,4-oxadiazoles is described. In situ preparation of various thiosemicarbazides by the reaction of different carboxylic acid hydrazides with trimethylsilyl isothiocyanate (TMSNCS), followed by cyclodesulfurization of thiosemicarbazides under basic conditions in the presence of I-2/KI resulted in 2-amino-1,3,4-oxadiazoles in high yields (79-94%).
- 出版日期2013
