Advances in the use of functional composites of beta-cyclodextrin in electrochemical sensors

作者：Niu Xiaohui; Mo Zunli; Yang Xing; Sun Mingyuan; Zhao Pan; Li Zhenliang; Ouyang Meixuan; Liu Zhenyu; Gao Huhu; Guo Ruibin; Liu Nijuan

来源：Microchimica Acta, 2018, 185(7): 328.

DOI：10.1007/s00604-018-2859-6

• Host-guest interaction
• Electrochemical recognition
• Modified electrodes

beta-Cyclodextrin (beta-CD) possess a hydrophobic inner cavity and a hydrophilic exterior surface. They exhibit excellent inclusion properties with the guest molecules that match cavity size, and beta-CD-based materials drew widespread attention in electrochemical sensors. The hydroxy groups at the edge of the cavity can form hydrogen bonds and undergo electrostatic and dipole-dipole interactions with other molecules. This review (with 109 refs.) reveals beta-CD-based detection mechanisms from the viewpoint of the size/shape-fit concept, and summarizes the current state of multiple electrochemical sensors based on the use of beta-CD and functionalized beta-CD such as carboxymethyl-beta-CD, mono-(6-ethanediamine-6-deoxy)-beta-CD, hydroxypropyl-beta-CD, thio-beta-cyclodextrin, and others.

• 出版日期2018-7
• 单位西北师范大学