摘要

Aim and objectivesTo explore risk factors for coronary artery disease (CAD) among middle-aged women in Taiwan. %26lt;br%26gt;BackgroundCoronary artery disease is a leading cause of death among females. Risk factors for CAD vary due to differences in ethnicity, gender and age. However, few studies have documented risk factors among middle-aged women. %26lt;br%26gt;DesignWe employed a cross-sectional, comparative study design. %26lt;br%26gt;MethodsSixty-five middle-aged women who were suspected of having CAD and who received cardiac catheterisation were purposively sampled and divided into a CAD group (with at least one coronary artery with %26gt;50% stenosis) and a control group, according to the results of catheterisation. Individual questionnaires regarding their medical history, blood test results, sociodemographic characteristics, metabolism, biomarkers and lifestyle risk factors were administered and quantified. %26lt;br%26gt;ResultsThe mean age of the 65 women (31 CAD and 34 controls) was 562years. Within the CAD group, there was a greater incidence of women with a history of diabetes mellitus (DM), increased fasting blood glucose and increased diastolic blood pressure. Comparatively fewer women within the CAD category used dietary supplements or had a lower level of physical activity. After adjusting for other confounders, it was discovered that women who used dietary supplements (OR=028; p=004) and engaged in physical activities (OR=016; p=002) were less likely to develop CAD. %26lt;br%26gt;ConclusionsUse of dietary supplements and engaging in physical activities can significantly predict the incidence of CAD among middle-aged women in Taiwan. %26lt;br%26gt;Relevance to clinical practiceMiddle-aged women should be encouraged to take appropriate dietary supplements and engage in physical activity in order to prevent CAD.

  • 出版日期2013-9
  • 单位长春大学

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