Markers of inflammation: data from the MOSAIC randomised trial of CPAP for minimally symptomatic OSA

作者：Stradling J R^*; Craig S E; Kohler M; Nicoll D; Ayers L; Nunn A J; Bratton D J

来源：Thorax, 2015, 70(2): 181-181.

DOI：10.1136/thoraxjnl-2014-205958

• Sleep apnoea
• Cytokine Biology

The Multi-centre Obstructive Sleep Apnoea Interventional Cardiovascular (MOSAIC) trial compared 6months of CPAP therapy, versus no CPAP, in 391 patients with minimally symptomatic obstructive sleep apnoea (OSA). We now report some exploratory outcomes, markers of systemic inflammation (interleukin 6 (IL-6), IL-10, C reactive protein, tumour necrosis factor). We found no consistent changes (all p values >0.13). Trial registration number: ISRCTN 34164388.

• 出版日期2015-2