科研之友
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摘要
We propose a general multigroup model for cholera dynamics that involves both direct and indirect transmission pathways and that incorporates spatial heterogeneity. Under biologically feasible conditions, we show that the basic reproduction number R-0 remains a sharp threshold for cholera dynamics in multigroup settings. We verify the analysis by numerical simulation results. We also perform an optimal control study to explore optimal vaccination strategy for cholera outbreaks.
- 出版日期2016-1
