Area dependent expression of ZNF312 in human fetal cerebral cortex

作者:Zhu, Hua; Yang, Yaojuan; Gao, Jun; Tao, Huaping; Qu, Chunsheng; Qu, Jia; Chen, Jieguang*
来源:Neuroscience Research, 2010, 68(1): 73-76.
DOI:10.1016/j.neures.2010.05.007

摘要

The human cerebral neocortex is divided into six layers consisting of specific neuronal cell types and connections To determine the distribution of cortical neurons during early development, we examined the expressions of layer-specific markers in human midterm fetal brains Layer V marker ZNF312 is expressed in most cortical areas, but not in the prospective somatosensory association area. Expression of layer IV marker ROR beta is also diminished in this region but Increased in the primary visual cortex, where expression of ZNF312 is reduced. O